Osteoradionecrosis (ORN) of the mandible is a severe complication of radiation therapy for head and neck cancer. In this case series, THANC analyzed their treatment and quality of life (QOL) outcomes over the past 6 years. We found a general lack of improvement in QOL, despite the restoration of an intact mandible, and suspect a negative relationship to the persistent effects of chemoradiotherapy.
A. S. Jacobson, J. Zevallos, M. Smith, C. L. Lazarus, H. Husaini, D. Okay, D. Buchbinder, M. Persky, M. L. Urken
International Journal of Oral and Maxillofacial Surgery