Extratumoral Invasion: A Unique Phenomenon of Aggressive Recurrent Oropharyngeal Squamous Cell Carcinoma


Seo GT, Greenberg L, Xing MH, Su V, Dowling E, Mundi N, Matloob A, Khorsandi AS, Chai RL, Urken ML, Brandwein-Weber M

American Journal of Otolaryngology

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This article presents eight cases of recurrent oropharyngeal cancer with extratumoral lymphovascular invasion or extratumoral perineural invasion. These features have received little attention as unique features of oropharyngeal squamous cell carcinoma, and this is the first series on these features in the recurrent setting.